increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0

http://metadb.riken.jp/0009152I129S4SvJaeBALBcC57BL6CBAKrastm4TyjKrasPtentm1HwuPtentm1HwuTgPdx1cre891Dam0KrasTgPdx1cre891DamKrastm4TyjPtentm1Hwu

increased pancreatic intraepithelial neoplasia incidence_Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transgene insertion 89.1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:2684318
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pdx1-cre)89.1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<+>|Tg(Pdx1-cre)89.1Dam|Kras<tm4Tyj>|Pten<tm1Hwu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009152

文献

http://purl.org/net/cito/citesAsAuthority

• Reginald. Hill, et.al., PTEN loss accelerates KrasG12D-induced pancreatic cancer development., Cancer research, 2010, 70
  http://rdf.ncbi.nlm.nih.gov/pubmed/20807812