increased pancreatic intraepithelial neoplasia incidence_Gt(ROSA)26Sor<tm2(Pik3ca*)Dsa>/Gt(ROSA)26Sor<+>,Tg(Ela1-cre/ERT)1Dam/0

http://metadb.riken.jp/0009152I129S6SvEvTacGtROSA26Sortm2Pik3caDsaGtROSA26SorTgEla1creERT1Dam0GtROSA26Sortm2Pik3caDsaGtROSA26SorTgEla1creERT1Dam

increased pancreatic intraepithelial neoplasia incidence_Gt(ROSA)26Sor<tm2(Pik3ca*)Dsa>/Gt(ROSA)26Sor<+>,Tg(Ela1-cre/ERT)1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:3821748

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(Pik3ca*)Dsa>/Gt(ROSA)26Sor<+>,Tg(Ela1-cre/ERT)1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm2(Pik3ca*)Dsa>|Gt(ROSA)26Sor<+>|Tg(Ela1-cre/ERT)1Dam

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009152

文献

http://purl.org/net/cito/citesAsAuthority

• Stefan. Eser, et.al., Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer., Cancer cell, 2013, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/23453624