increased pancreas tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(Ela1-cre/ERT)1Dam/0

http://metadb.riken.jp/0009153I129S4SvJaeKrastm4TyjKrasTgEla1creERT1Dam0TgEla1creERT1DamKrastm4TyjKras

increased pancreas tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(Ela1-cre/ERT)1Dam/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• transgene insertion 1, Douglas A Melton
  http://metadb.riken.jp/db/mgi_rdf/MGI:3821748

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Tg(Ela1-cre/ERT)1Dam/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ela1-cre/ERT)1Dam|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreas tumor incidence
  http://purl.obolibrary.org/obo/MP_0009153

文献

http://purl.org/net/cito/citesAsAuthority

• Stefan. Eser, et.al., Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer., Cancer cell, 2013, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/23453624