increased pancreas tumor incidence_Apc<tm2Rak>/Apc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0

http://metadb.riken.jp/0009153I129Sv129P2OlaHsdC57BL6JFVBNSJLApctm2RakApcTrp53tm1BrnTrp53tm1BrnTgPdx1cre6Tuv0Apctm2RakApcTrp53tm1BrnTgPdx1cre6Tuv

increased pancreas tumor incidence_Apc<tm2Rak>/Apc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 6, David A Tuveson
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437123
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm2Rak>/Apc<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Pdx1-cre)6Tuv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apc<tm2Rak>|Apc<+>|Trp53<tm1Brn>|Tg(Pdx1-cre)6Tuv

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129P2/OlaHsd * C57BL/6J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreas tumor incidence
  http://purl.obolibrary.org/obo/MP_0009153

文献

http://purl.org/net/cito/citesAsAuthority

• T-L. Kuo, et.al., APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice., Oncogene, 2016, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/26411367