decreased pancreatic islet number_Apc<tm2Rak>/Apc<tm2Rak>,Tg(Pdx1-cre)6Tuv/0

http://metadb.riken.jp/0009168I129SvC57BL6JFVBNSJLApctm2RakApctm2RakTgPdx1cre6Tuv0TgPdx1cre6TuvApctm2Rak

decreased pancreatic islet number_Apc<tm2Rak>/Apc<tm2Rak>,Tg(Pdx1-cre)6Tuv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039
• transgene insertion 6, David A Tuveson
  http://metadb.riken.jp/db/mgi_rdf/MGI:5437123

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm2Rak>/Apc<tm2Rak>,Tg(Pdx1-cre)6Tuv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pdx1-cre)6Tuv|Apc<tm2Rak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6J * FVB/N * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased pancreatic islet number
  http://purl.obolibrary.org/obo/MP_0009168

文献

http://purl.org/net/cito/citesAsAuthority

• T-L. Kuo, et.al., APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice., Oncogene, 2016, 35
  http://rdf.ncbi.nlm.nih.gov/pubmed/26411367