absent pancreatic beta cells_Tfam<tm1Lrsn>/Tfam<tm1Lrsn>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0009174I129S1Sv129X1SvJC57BL6DBATfamtm1LrsnTfamtm1LrsnTgIns2cre25Mgn0Tfamtm1LrsnTgIns2cre25Mgn

absent pancreatic beta cells_Tfam<tm1Lrsn>/Tfam<tm1Lrsn>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transcription factor A, mitochondrial
  http://metadb.riken.jp/db/mgi_rdf/MGI:107810
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tfam<tm1Lrsn>/Tfam<tm1Lrsn>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tfam<tm1Lrsn>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• absent pancreatic beta cells
  http://purl.obolibrary.org/obo/MP_0009174

文献

http://purl.org/net/cito/citesAsAuthority

• J P. Silva, et.al., Impaired insulin secretion and beta-cell loss in tissue-specific knockout mice with mitochondrial diabetes., Nature genetics, 2000, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/11062475