increased pancreatic alpha cell number_Gcgr<tm2.1Mjch>/Gcgr<tm2.1Mjch>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0009176IC57BL6DBASJLGcgrtm21MjchGcgrtm21MjchTgAlbcre21Mgn0TgAlbcre21MgnGcgrtm21Mjch

increased pancreatic alpha cell number_Gcgr<tm2.1Mjch>/Gcgr<tm2.1Mjch>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glucagon receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:99572
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gcgr<tm2.1Mjch>/Gcgr<tm2.1Mjch>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Gcgr<tm2.1Mjch>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * DBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pancreatic alpha cell number
  http://purl.obolibrary.org/obo/MP_0009176

文献

http://purl.org/net/cito/citesAsAuthority

• Christine. Longuet, et.al., Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: evidence for a circulating α-cell growth factor., Diabetes, 2013, 62
  http://rdf.ncbi.nlm.nih.gov/pubmed/23160527