decreased PP cell number_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>,Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>

http://metadb.riken.jp/0009186I129129X1SvJC57BL6JNkx22tm1JlrNkx22tm1JlrNkx61tm1JlrNkx61tm1JlrNkx22tm1JlrNkx61tm1Jlr

decreased PP cell number_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>,Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• NK2 homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:97347
• NK6 homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1206039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>,Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nkx2-2<tm1Jlr>|Nkx6-1<tm1Jlr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased PP cell number
  http://purl.obolibrary.org/obo/MP_0009186

文献

http://purl.org/net/cito/citesAsAuthority

• M. Sander, et.al., Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas., Development (Cambridge, England), 2000, 127
  http://rdf.ncbi.nlm.nih.gov/pubmed/11076772