M. Sander, et.al., Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas., Development (Cambridge, England), 2000, 127

http://rdf.ncbi.nlm.nih.gov/pubmed/11076772

M. Sander, et.al., Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas., Development (Cambridge, England), 2000, 127

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386119

class

http://purl.org/net/cito/citesAsAuthority

• Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/db/mgi_rdf/MGI:2386119

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased PP cell number_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>,Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/0009186I129129X1SvJC57BL6JNkx22tm1JlrNkx22tm1JlrNkx61tm1JlrNkx61tm1JlrNkx22tm1JlrNkx61tm1Jlr
• decreased pancreatic beta cell number_Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/0003339I129C57BL6JNkx61tm1JlrNkx61tm1JlrNkx61tm1Jlr
• disorganized pancreatic islets_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>,Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/0009254I129129X1SvJC57BL6JNkx22tm1JlrNkx22tm1JlrNkx61tm1JlrNkx61tm1JlrNkx22tm1JlrNkx61tm1Jlr
• decreased pancreatic alpha cell number_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>,Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/0009177I129129X1SvJC57BL6JNkx22tm1JlrNkx22tm1JlrNkx61tm1JlrNkx61tm1JlrNkx22tm1JlrNkx61tm1Jlr
• small pancreatic islets_Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/0009172I129C57BL6JNkx61tm1JlrNkx61tm1JlrNkx61tm1Jlr
• decreased pancreatic beta cell number_Nkx2-2<tm1Jlr>/Nkx2-2<tm1Jlr>,Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/0003339I129129X1SvJC57BL6JNkx22tm1JlrNkx22tm1JlrNkx61tm1JlrNkx61tm1JlrNkx22tm1JlrNkx61tm1Jlr
• decreased insulin secretion_Nkx6-1<tm1Jlr>/Nkx6-1<tm1Jlr>
  http://metadb.riken.jp/0003059I129C57BL6JNkx61tm1JlrNkx61tm1JlrNkx61tm1Jlr