increased prostate intraepithelial neoplasia incidence_Pten<tm1.1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>

http://metadb.riken.jp/0009219I129S4SvJaeC57BL6DBA2Ptentm11HwuPtenTmprss2tm21ETV1ShoTmprss2tm21ETV1ShoPtentm11HwuTmprss2tm21ETV1ShoPten

increased prostate intraepithelial neoplasia incidence_Pten<tm1.1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transmembrane protease, serine 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354381

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1.1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1.1Hwu>|Tmprss2<tm2.1(ETV1)Sho>|Pten<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate intraepithelial neoplasia incidence
  http://purl.obolibrary.org/obo/MP_0009219

文献

http://purl.org/net/cito/citesAsAuthority

• Esther. Baena, et.al., ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients., Genes & development, 2013, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/23512661