Esther. Baena, et.al., ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients., Genes & development, 2013, 27

http://rdf.ncbi.nlm.nih.gov/pubmed/23512661

Esther. Baena, et.al., ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients., Genes & development, 2013, 27

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tmprss2<tm1.1(ERG)Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578606
• Tmprss2<tm2.1(ETV1)Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578607
• Tmprss2<tm3Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578610
• Erg<tm1.1Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578611
• Del(16Tmprss2-Erg)1Sho
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578624

class

http://purl.org/net/cito/citesAsAuthority

• Tmprss2<tm1.1(ERG)Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578606
• Tmprss2<tm2.1(ETV1)Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578607
• Tmprss2<tm3Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578610
• Erg<tm1.1Sho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578611
• Del(16Tmprss2-Erg)1Sho
  http://metadb.riken.jp/db/mgi_rdf/MGI:5578624

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• prostate gland hyperplasia_Del(16Tmprss2-Erg)1Sho/Del(16Tmprss2-Erg)1Sho
  http://metadb.riken.jp/0000659IC57BL6DBA2Del16Tmprss2Erg1ShoDel16Tmprss2Erg1ShoDel16Tmprss2Erg1Sho
• premature death_Pten<tm1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0002083I129S4SvJaeC57BL6DBA2Ptentm1HwuPtenTmprss2tm21ETV1ShoTmprss2tm21ETV1ShoTgPbsncre4Prb0Tmprss2tm21ETV1ShoTgPbsncre4PrbPtentm1HwuPten
• prostate gland inflammation_Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>
  http://metadb.riken.jp/0003608IC57BL6DBA2Tmprss2tm21ETV1ShoTmprss2tm21ETV1ShoTmprss2tm21ETV1Sho
• increased prostate intraepithelial neoplasia incidence_Del(16Tmprss2-Erg)1Sho/Del(16Tmprss2-Erg)1Sho,Pten<tm1.1Hwu>/Pten<+>
  http://metadb.riken.jp/0009219I129S4SvJaeC57BL6DBA2Del16Tmprss2Erg1ShoDel16Tmprss2Erg1ShoPtentm11HwuPtenPtentm11HwuDel16Tmprss2Erg1ShoPten
• increased prostate intraepithelial neoplasia incidence_Pten<tm1.1Hwu>/Pten<+>,Tmprss2<tm1.1(ERG)Sho>/Tmprss2<tm1.1(ERG)Sho>
  http://metadb.riken.jp/0009219I129S4SvJaeC57BL6DBA2Ptentm11HwuPtenTmprss2tm11ERGShoTmprss2tm11ERGShoPtentm11HwuPtenTmprss2tm11ERGSho
• increased prostate intraepithelial neoplasia incidence_Pten<tm1.1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>
  http://metadb.riken.jp/0009219I129S4SvJaeC57BL6DBA2Ptentm11HwuPtenTmprss2tm21ETV1ShoTmprss2tm21ETV1ShoPtentm11HwuTmprss2tm21ETV1ShoPten
他6件を見る
• increased prostate intraepithelial neoplasia incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009219I129S4SvJaeC57BL6DBA2Ptentm1HwuPtentm1HwuTgPbsncre4Prb0Ptentm1HwuTgPbsncre4Prb
• increased prostate gland adenocarcinoma incidence_Erg<tm1.1Sho>/Erg<tm1.1Sho>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tmprss2<tm3Sho>/Tmprss2<tm3Sho>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009220I129S4SvJaeC57BL6DBA2Ergtm11ShoErgtm11ShoPtentm1HwuPtentm1HwuTmprss2tm3ShoTmprss2tm3ShoTgPbsncre4Prb0Tmprss2tm3ShoPtentm1HwuErgtm11ShoTgPbsncre4Prb
• increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009220I129S4SvJaeC57BL6DBA2Ptentm1HwuPtenTmprss2tm21ETV1ShoTmprss2tm21ETV1ShoTgPbsncre4Prb0Tmprss2tm21ETV1ShoTgPbsncre4PrbPtentm1HwuPten
• increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009220I129S4SvJaeC57BL6DBA2Ptentm1HwuPtentm1HwuTgPbsncre4Prb0Ptentm1HwuTgPbsncre4Prb
• prostate gland cysts_Pten<tm1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>,Tg(Pbsn-cre)4Prb/0
  http://metadb.riken.jp/0009737I129S4SvJaeC57BL6DBA2Ptentm1HwuPtenTmprss2tm21ETV1ShoTmprss2tm21ETV1ShoTgPbsncre4Prb0Tmprss2tm21ETV1ShoTgPbsncre4PrbPtentm1HwuPten
• abnormal testosterone level_Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>
  http://metadb.riken.jp/0011385IC57BL6DBA2Tmprss2tm21ETV1ShoTmprss2tm21ETV1ShoTmprss2tm21ETV1Sho