increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>,Tg(Pbsn-cre)4Prb/0

http://metadb.riken.jp/0009220I129S4SvJaeC57BL6DBA2Ptentm1HwuPtenTmprss2tm21ETV1ShoTmprss2tm21ETV1ShoTgPbsncre4Prb0Tmprss2tm21ETV1ShoTgPbsncre4PrbPtentm1HwuPten

increased prostate gland adenocarcinoma incidence_Pten<tm1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>,Tg(Pbsn-cre)4Prb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 4, Pradip Roy-Burman
  http://metadb.riken.jp/db/mgi_rdf/MGI:2388169
• transmembrane protease, serine 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354381
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<+>,Tmprss2<tm2.1(ETV1)Sho>/Tmprss2<tm2.1(ETV1)Sho>,Tg(Pbsn-cre)4Prb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tmprss2<tm2.1(ETV1)Sho>|Tg(Pbsn-cre)4Prb|Pten<tm1Hwu>|Pten<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased prostate gland adenocarcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009220

文献

http://purl.org/net/cito/citesAsAuthority

• Esther. Baena, et.al., ETV1 directs androgen metabolism and confers aggressive prostate cancer in targeted mice and patients., Genes & development, 2013, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/23512661