disorganized pancreatic islets_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0009254I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn

disorganized pancreatic islets_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pancreatic and duodenal homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102851
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdx1<tm1Cvw>|Pdx1<tm4Cvw>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• disorganized pancreatic islets
  http://purl.obolibrary.org/obo/MP_0009254

文献

http://purl.org/net/cito/citesAsAuthority

• Maureen. Gannon, et.al., pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis., Developmental biology, 2008, 314
  http://rdf.ncbi.nlm.nih.gov/pubmed/18155690