Maureen. Gannon, et.al., pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis., Developmental biology, 2008, 314

http://rdf.ncbi.nlm.nih.gov/pubmed/18155690

Maureen. Gannon, et.al., pdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasis., Developmental biology, 2008, 314

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Pdx1<tm4Cvw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702084

class

http://purl.org/net/cito/citesAsAuthority

• Pdx1<tm4Cvw>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3702084

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased circulating insulin level_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0002727I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn
• abnormal pancreas morphology_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0001944I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn
• disorganized pancreatic islets_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009254I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn
• no abnormal phenotype detected_Pdx1<tm4Cvw>/Pdx1<tm4Cvw>
  http://metadb.riken.jp/0002169I129S1Sv129X1SvJBlackSwissPdx1tm4CvwPdx1tm4CvwPdx1tm4Cvw
• decreased pancreatic beta cell number_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0003339I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn
• impaired glucose tolerance_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005293I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn
• increased circulating glucose level_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0005559I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn
• increased pancreatic delta cell number_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009180I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn
• increased pancreatic alpha cell number_Pdx1<tm1Cvw>/Pdx1<tm4Cvw>,Tg(Ins2-cre)25Mgn/0
  http://metadb.riken.jp/0009176I129S1Sv129X1SvJBlackSwissC57BL6DBAPdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn0Pdx1tm1CvwPdx1tm4CvwTgIns2cre25Mgn