increased histiocytic sarcoma incidence_Mdm2<tm3.1Glo>/Mdm2<tm3.1Glo>,Trp53<tm3.1Glo>/Trp53<+>

http://metadb.riken.jp/0009321B6129SMdm2tm31GloTrp53tm31GloMdm2tm31GloMdm2tm31GloTrp53tm31GloTrp53Trp53Trp53tm31GloMdm2tm31Glo

increased histiocytic sarcoma incidence_Mdm2<tm3.1Glo>/Mdm2<tm3.1Glo>,Trp53<tm3.1Glo>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformed mouse 3T3 cell double minute 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96952
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mdm2<tm3.1Glo>/Mdm2<tm3.1Glo>,Trp53<tm3.1Glo>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<+>|Trp53<tm3.1Glo>|Mdm2<tm3.1Glo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129S-Mdm2<tm3.1Glo> Trp53<tm3.1Glo>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased histiocytic sarcoma incidence
  http://purl.obolibrary.org/obo/MP_0009321

文献

http://purl.org/net/cito/citesAsAuthority

• Sean M. Post, et.al., A high-frequency regulatory polymorphism in the p53 pathway accelerates tumor development., Cancer cell, 2010, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/20832750