environmentally induced seizures_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0

http://metadb.riken.jp/0009358I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher

environmentally induced seizures_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:109482
• transgene insertion 2, Max-Planck-Institute of Neurobiology
  http://metadb.riken.jp/db/mgi_rdf/MGI:2137514

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Pcp2-cre)2Mpin|Cacna1a<tm1.1Sher>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• environmentally induced seizures
  http://purl.obolibrary.org/obo/MP_0009358

文献

http://purl.org/net/cito/citesAsAuthority

• Melanie D. Mark, et.al., Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/21411672