Melanie D. Mark, et.al., Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31

http://rdf.ncbi.nlm.nih.gov/pubmed/21411672

Melanie D. Mark, et.al., Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, 31

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Cacna1a<tm1.2Sher>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4949729
• Cacna1a<tm1.1Sher>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4949728

class

http://purl.org/net/cito/citesAsAuthority

• Cacna1a<tm1.2Sher>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4949729
• Cacna1a<tm1.1Sher>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4949728

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• no abnormal phenotype detected_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>
  http://metadb.riken.jp/0002169I129S4SvJaeCacna1atm11SherCacna1atm11SherCacna1atm11Sher
• environmentally induced seizures_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0009358I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• decreased grip strength_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0010053I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• impaired coordination_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001405I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• abnormal inhibitory postsynaptic currents_Cacna1a<tm1.2Sher>/Cacna1a<tm1.2Sher>
  http://metadb.riken.jp/0002945I129S4SvJaeCacna1atm12SherCacna1atm12SherCacna1atm12Sher
• ataxia_Cacna1a<tm1.2Sher>/Cacna1a<tm1.2Sher>
  http://metadb.riken.jp/0001393I129S4SvJaeCacna1atm12SherCacna1atm12SherCacna1atm12Sher
• thin cerebellar granule layer_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0006099I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• decreased body size_Cacna1a<tm1.2Sher>/Cacna1a<tm1.2Sher>
  http://metadb.riken.jp/0001265I129S4SvJaeCacna1atm12SherCacna1atm12SherCacna1atm12Sher
• abnormal inhibitory postsynaptic currents_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0002945I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• abnormal channel response_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0003484I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• abnormal spike wave discharge_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0008840I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• ataxia_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001393I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• premature death_Cacna1a<tm1.2Sher>/Cacna1a<tm1.2Sher>
  http://metadb.riken.jp/0002083I129S4SvJaeCacna1atm12SherCacna1atm12SherCacna1atm12Sher
• decreased body weight_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0001262I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• abnormal action potential_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0005402I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• small cerebellum_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0000852I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• abnormal seizure response to inducing agent_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0009357I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• thin cerebellar molecular layer_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0000890I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher
• seizures_Cacna1a<tm1.2Sher>/Cacna1a<tm1.2Sher>
  http://metadb.riken.jp/0002064I129S4SvJaeCacna1atm12SherCacna1atm12SherCacna1atm12Sher
• absence seizures_Cacna1a<tm1.1Sher>/Cacna1a<tm1.1Sher>,Tg(Pcp2-cre)2Mpin/0
  http://metadb.riken.jp/0003216I129S1Sv129S4SvJae129X1SvJCacna1atm11SherCacna1atm11SherTgPcp2cre2Mpin0TgPcp2cre2MpinCacna1atm11Sher