hypergranulosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>

http://metadb.riken.jp/0009600I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt10tm2TmmKrt10tm2TmmKrt10tm2TmmKrt2tm1aKOMPWtsi

hypergranulosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• keratin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96699
• keratin 10
  http://metadb.riken.jp/db/mgi_rdf/MGI:96685

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Krt10<tm2Tmm>|Krt2<tm1a(KOMP)Wtsi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * BALB/c * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• hypergranulosis
  http://purl.obolibrary.org/obo/MP_0009600

文献

http://purl.org/net/cito/citesAsAuthority

• Heinz. Fischer, et.al., Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation., The Journal of investigative dermatology, 2014, 134
  http://rdf.ncbi.nlm.nih.gov/pubmed/24751727