Heinz. Fischer, et.al., Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation., The Journal of investigative dermatology, 2014, 134

http://rdf.ncbi.nlm.nih.gov/pubmed/24751727

Heinz. Fischer, et.al., Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation., The Journal of investigative dermatology, 2014, 134

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hyperkeratosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0001242I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt10tm2TmmKrt10tm2TmmKrt10tm2TmmKrt2tm1aKOMPWtsi
• epidermal hyperplasia_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0001222I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt10tm2TmmKrt10tm2TmmKrt10tm2TmmKrt2tm1aKOMPWtsi
• scaly skin_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001192IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• abnormal keratinocyte differentiation_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0002656IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• hypergranulosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0009600IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• impaired skin barrier function_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0002796IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• increased ear pigmentation_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0011278IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• skin inflammation_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0004947IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• hypergranulosis_Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0009600I129P2OlaHsdBALBcC57BL6NKrt10tm2TmmKrt10tm2TmmKrt10tm2Tmm
• abnormal epidermis suprabasal layer morphology_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001233I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• epidermal hyperplasia_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001222I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• abnormal epidermis stratum corneum morphology_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001240IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• increased keratinocyte proliferation_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0009583IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• hypergranulosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0009600I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt10tm2TmmKrt10tm2TmmKrt10tm2TmmKrt2tm1aKOMPWtsi
• abnormal epidermis suprabasal layer morphology_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0001233I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt10tm2TmmKrt10tm2TmmKrt10tm2TmmKrt2tm1aKOMPWtsi
• thick epidermis stratum granulosum_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0009599IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• hypergranulosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0009600I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• epidermal hyperplasia_Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0001222I129P2OlaHsdBALBcC57BL6NKrt10tm2TmmKrt10tm2TmmKrt10tm2Tmm
• orthokeratosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0009675IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• hyperkeratosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001242IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• acanthosis_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001874IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi
• abnormal epidermis suprabasal layer morphology_Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0001233I129P2OlaHsdBALBcC57BL6NKrt10tm2TmmKrt10tm2TmmKrt10tm2Tmm
• scaly skin_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>,Krt10<tm2Tmm>/Krt10<tm2Tmm>
  http://metadb.riken.jp/0001192I129P2OlaHsdBALBcC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt10tm2TmmKrt10tm2TmmKrt10tm2TmmKrt2tm1aKOMPWtsi
• abnormal epidermis suprabasal layer morphology_Krt2<tm1a(KOMP)Wtsi>/Krt2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001233IC57BL6NKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsiKrt2tm1aKOMPWtsi