increased skin squamous cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre/ERT)20Efu/0

http://metadb.riken.jp/0009704I129P2OlaHsd129S4SvJaeCD1Krastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgKRT14creERT20Efu0Krastm4TyjKrasTrp53tm1BrnTgKRT14creERT20Efu

increased skin squamous cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre/ERT)20Efu/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 20, Elaine Fuchs
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446592
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre/ERT)20Efu/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kras<tm4Tyj>|Kras<+>|Trp53<tm1Brn>|Tg(KRT14-cre/ERT)20Efu

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin squamous cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009704

文献

http://purl.org/net/cito/citesAsAuthority

• Gaëlle. Lapouge, et.al., Identifying the cellular origin of squamous skin tumors., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21502497