Gaëlle. Lapouge, et.al., Identifying the cellular origin of squamous skin tumors., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

http://rdf.ncbi.nlm.nih.gov/pubmed/21502497

Gaëlle. Lapouge, et.al., Identifying the cellular origin of squamous skin tumors., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(IVL-cre/ERT2)1Blpn
  http://metadb.riken.jp/db/mgi_rdf/MGI:4999984

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased cell proliferation_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0000351I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• enlarged sebaceous gland_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0000652I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• skin lesions_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre/ERT)20Efu/0
  http://metadb.riken.jp/0001212I129P2OlaHsd129S4SvJaeCD1Krastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgKRT14creERT20Efu0Krastm4TyjKrasTrp53tm1BrnTgKRT14creERT20Efu
• thick epidermis_Kras<tm4Tyj>/Kras<+>,Tg(IVL-cre/ERT2)1Blpn/0
  http://metadb.riken.jp/0001219I129S4SvJaeC57BL6Krastm4TyjKrasTgIVLcreERT21Blpn0TgIVLcreERT21BlpnKrastm4TyjKras
• epidermal hyperplasia_Kras<tm4Tyj>/Kras<+>,Tg(IVL-cre/ERT2)1Blpn/0
  http://metadb.riken.jp/0001222I129S4SvJaeC57BL6Krastm4TyjKrasTgIVLcreERT21Blpn0TgIVLcreERT21BlpnKrastm4TyjKras
• increased carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0002038I129P2OlaHsd129S4SvJae129S6SvEvTacKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrt19tm1creERTGguKrt19Krt19Trp53tm1BrnKrt19tm1creERTGguKrasKrastm4Tyj
他18件を見る
• increased skin papilloma incidence_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0002051I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• increased skin papilloma incidence_Kras<tm4Tyj>/Kras<+>,Tg(Krt1-15-cre/PGR)22Cot/0
  http://metadb.riken.jp/0002051I129S4SvJaeC57BL6JSJLJKrastm4TyjKrasTgKrt115crePGR22Cot0TgKrt115crePGR22CotKrastm4TyjKras
• increased skin papilloma incidence_Kras<tm4Tyj>/Kras<+>,Tg(IVL-cre/ERT2)1Blpn/0
  http://metadb.riken.jp/0002051I129S4SvJaeC57BL6Krastm4TyjKrasTgIVLcreERT21Blpn0TgIVLcreERT21BlpnKrastm4TyjKras
• increased lip tumor incidence_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0003780I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• increased lip tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(Krt1-15-cre/PGR)22Cot/0
  http://metadb.riken.jp/0003780I129S4SvJaeC57BL6JSJLJKrastm4TyjKrasTgKrt115crePGR22Cot0TgKrt115crePGR22CotKrastm4TyjKras
• increased lip tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(IVL-cre/ERT2)1Blpn/0
  http://metadb.riken.jp/0003780I129S4SvJaeC57BL6Krastm4TyjKrasTgIVLcreERT21Blpn0TgIVLcreERT21BlpnKrastm4TyjKras
• increased facial tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(Krt1-15-cre/PGR)22Cot/0
  http://metadb.riken.jp/0008018I129S4SvJaeC57BL6JSJLJKrastm4TyjKrasTgKrt115crePGR22Cot0TgKrt115crePGR22CotKrastm4TyjKras
• increased facial tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(IVL-cre/ERT2)1Blpn/0
  http://metadb.riken.jp/0008018I129S4SvJaeC57BL6Krastm4TyjKrasTgIVLcreERT21Blpn0TgIVLcreERT21BlpnKrastm4TyjKras
• abnormal skin sebaceous gland morphology_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0009535I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• increased skin squamous cell carcinoma incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(KRT14-cre/ERT)20Efu/0
  http://metadb.riken.jp/0009704I129P2OlaHsd129S4SvJaeCD1Krastm4TyjKrasTrp53tm1BrnTrp53tm1BrnTgKRT14creERT20Efu0Krastm4TyjKrasTrp53tm1BrnTgKRT14creERT20Efu
• abnormal hair follicle bulge morphology_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0009759I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• sebaceous gland hyperplasia_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0009794I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• increased gastrointestinal tumor incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0010279I129P2OlaHsd129S4SvJae129S6SvEvTacKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrt19tm1creERTGguKrt19Krt19Trp53tm1BrnKrt19tm1creERTGguKrasKrastm4Tyj
• increased skin tumor incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0010300I129P2OlaHsd129S4SvJae129S6SvEvTacKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrt19tm1creERTGguKrt19Krt19Trp53tm1BrnKrt19tm1creERTGguKrasKrastm4Tyj
• increased skin tumor incidence_Kras<tm4Tyj>/Kras<+>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0010300I129S4SvJae129S6SvEvTacKrastm4TyjKrasKrt19tm1creERTGguKrt19Krastm4TyjKrt19tm1creERTGguKrasKrt19
• increased skin tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(Krt1-15-cre/PGR)22Cot/0
  http://metadb.riken.jp/0010300I129S4SvJaeC57BL6JSJLJKrastm4TyjKrasTgKrt115crePGR22Cot0TgKrt115crePGR22CotKrastm4TyjKras
• increased skin tumor incidence_Kras<tm4Tyj>/Kras<+>,Tg(IVL-cre/ERT2)1Blpn/0
  http://metadb.riken.jp/0010300I129S4SvJaeC57BL6Krastm4TyjKrasTgIVLcreERT21Blpn0TgIVLcreERT21BlpnKrastm4TyjKras
• lethality, complete penetrance_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>
  http://metadb.riken.jp/0011400I129P2OlaHsd129S4SvJae129S6SvEvTacKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrt19tm1creERTGguKrt19Krt19Trp53tm1BrnKrt19tm1creERTGguKrasKrastm4Tyj

class

http://purl.org/net/cito/citesAsAuthority

• Tg(IVL-cre/ERT2)1Blpn
  http://metadb.riken.jp/db/mgi_rdf/MGI:4999984