increased skin squamous cell carcinoma incidence_Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre)8Brn/0

http://metadb.riken.jp/0009704I129S1SvC57BL6FVBNGrhl3tm1JaneGrhl3tm31JaneTgKRT14cre8Brn0Grhl3tm31JaneTgKRT14cre8BrnGrhl3tm1Jane

increased skin squamous cell carcinoma incidence_Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre)8Brn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 8, Anton Berns
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177242
• grainyhead-like 3 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:2655333

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Grhl3<tm1Jane>/Grhl3<tm3.1Jane>,Tg(KRT14-cre)8Brn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Grhl3<tm3.1Jane>|Tg(KRT14-cre)8Brn|Grhl3<tm1Jane>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin squamous cell carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0009704

文献

http://purl.org/net/cito/citesAsAuthority

• Charbel. Darido, et.al., Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis., Cancer cell, 2011, 20
  http://rdf.ncbi.nlm.nih.gov/pubmed/22094257