increased sensitivity to induced morbidity/mortality_Tnf<tm1.1Sned>/Tnf<tm1.1Sned>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0009763I129129P2OlaHsdC57BL6Tnftm11SnedTnftm11SnedLyz2tm1creIfoLyz2Lyz2tm1creIfoLyz2Tnftm11Sned

increased sensitivity to induced morbidity/mortality_Tnf<tm1.1Sned>/Tnf<tm1.1Sned>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104798
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tnf<tm1.1Sned>/Tnf<tm1.1Sned>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyz2<tm1(cre)Ifo>|Lyz2<+>|Tnf<tm1.1Sned>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to induced morbidity/mortality
  http://purl.obolibrary.org/obo/MP_0009763

文献

http://purl.org/net/cito/citesAsAuthority

• Sergei I. Grivennikov, et.al., Distinct and nonredundant in vivo functions of TNF produced by t cells and macrophages/neutrophils: protective and deleterious effects., Immunity, 2005, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/15664162