increased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm2Gkl>/Tnfrsf1a<+>,Tg(Vil1-cre)997Gum/0

http://metadb.riken.jp/0009763I129SSvEvC57BL6JSJLTnfrsf1atm2GklTnfrsf1aTgVil1cre997Gum0Tnfrsf1atm2GklTnfrsf1aTgVil1cre997Gum

increased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm2Gkl>/Tnfrsf1a<+>,Tg(Vil1-cre)997Gum/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884
• transgene insertion 997, Deborah L Gumucio
  http://metadb.riken.jp/db/mgi_rdf/MGI:2446957

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tnfrsf1a<tm2Gkl>/Tnfrsf1a<+>,Tg(Vil1-cre)997Gum/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnfrsf1a<tm2Gkl>|Tnfrsf1a<+>|Tg(Vil1-cre)997Gum

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to induced morbidity/mortality
  http://purl.obolibrary.org/obo/MP_0009763

文献

http://purl.org/net/cito/citesAsAuthority

• Filip. Van Hauwermeiren, et.al., Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium., The Journal of clinical investigation, 2013, 123
  http://rdf.ncbi.nlm.nih.gov/pubmed/23676465