Filip. Van Hauwermeiren, et.al., Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium., The Journal of clinical investigation, 2013, 123

http://rdf.ncbi.nlm.nih.gov/pubmed/23676465

Filip. Van Hauwermeiren, et.al., Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium., The Journal of clinical investigation, 2013, 123

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tnfrsf1a<tm3.2Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5572950
• Tnfrsf1a<tm4.1(TNFRSF1A)Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5572951
• Tnfrsf1a<tm3.1Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5572949

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• impaired humoral immune response_Tnfrsf1a<tm1Imx>/Tnfrsf1a<tm1Imx>
  http://metadb.riken.jp/0020154IC57BL6Tnfrsf1atm1ImxTnfrsf1atm1ImxTnfrsf1atm1Imx
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0009764I129S2SvPasTnfrsf1atm1MakTnfrsf1atm1MakTnfrsf1atm1Mak
• decreased circulating interleukin-6 level_Tnfrsf1a<tm1Mak>/Tnfrsf1a<+>
  http://metadb.riken.jp/0008597I129S2SvPasTnfrsf1atm1MakTnfrsf1aTnfrsf1atm1MakTnfrsf1a
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm4.1(TNFRSF1A)Gkl>/Tnfrsf1a<+>
  http://metadb.riken.jp/0009764I129P2OlaHsdTnfrsf1atm41TNFRSF1AGklTnfrsf1aTnfrsf1atm41TNFRSF1AGklTnfrsf1a
• abnormal intestine physiology_Tnfrsf1a<tm2Gkl>/Tnfrsf1a<+>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0010155I129SSvEvC57BL6JSJLTnfrsf1atm2GklTnfrsf1aTgVil1cre997Gum0Tnfrsf1atm2GklTnfrsf1aTgVil1cre997Gum
• increased sensitivity to induced cell death_Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0008943I129S2SvPasTnfrsf1atm1MakTnfrsf1atm1MakTnfrsf1atm1Mak
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm3.1Gkl>/Tnfrsf1a<+>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0009764I129P2OlaHsdC57BL6C57BL6JSJLTnfrsf1atm31GklTnfrsf1aTgVil1cre997Gum0Tnfrsf1aTnfrsf1atm31GklTgVil1cre997Gum
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm3.1Gkl>/Tnfrsf1a<+>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003638I129P2OlaHsdC57BL6C57BL6JSJLTnfrsf1atm31GklTnfrsf1aTgVil1cre997Gum0Tnfrsf1aTnfrsf1atm31GklTgVil1cre997Gum
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0003638I129S2SvPasTnfrsf1atm1MakTnfrsf1atm1MakTnfrsf1atm1Mak
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm1Imx>/Tnfrsf1a<tm1Imx>
  http://metadb.riken.jp/0009764IC57BL6Tnfrsf1atm1ImxTnfrsf1atm1ImxTnfrsf1atm1Imx
• increased susceptibility to bacterial infection induced morbidity/mortality_Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0009788I129S2SvPasTnfrsf1atm1MakTnfrsf1atm1MakTnfrsf1atm1Mak
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm1Blt>/Tnfrsf1a<tm1Blt>
  http://metadb.riken.jp/0009764I129P2OlaHsdTnfrsf1atm1BltTnfrsf1atm1BltTnfrsf1atm1Blt
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm1Imx>/Tnfrsf1a<+>
  http://metadb.riken.jp/0009764IC57BL6Tnfrsf1atm1ImxTnfrsf1aTnfrsf1aTnfrsf1atm1Imx
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm1Blt>/Tnfrsf1a<+>
  http://metadb.riken.jp/0009764I129P2OlaHsdTnfrsf1atm1BltTnfrsf1aTnfrsf1atm1BltTnfrsf1a
• increased susceptibility to bacterial infection induced morbidity/mortality_Tnfrsf1a<tm1Imx>/Tnfrsf1a<tm1Imx>
  http://metadb.riken.jp/0009788IC57BL6Tnfrsf1atm1ImxTnfrsf1atm1ImxTnfrsf1atm1Imx
• decreased circulating interleukin-6 level_Tnfrsf1a<tm1Imx>/Tnfrsf1a<+>
  http://metadb.riken.jp/0008597IC57BL6Tnfrsf1atm1ImxTnfrsf1aTnfrsf1aTnfrsf1atm1Imx
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm1Mak>/Tnfrsf1a<+>
  http://metadb.riken.jp/0009764I129S2SvPasTnfrsf1atm1MakTnfrsf1aTnfrsf1atm1MakTnfrsf1a
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm1Imx>/Tnfrsf1a<tm1Imx>
  http://metadb.riken.jp/0003638IC57BL6Tnfrsf1atm1ImxTnfrsf1atm1ImxTnfrsf1atm1Imx
• impaired humoral immune response_Tnfrsf1a<tm1Blt>/Tnfrsf1a<tm1Blt>
  http://metadb.riken.jp/0020154I129P2OlaHsdTnfrsf1atm1BltTnfrsf1atm1BltTnfrsf1atm1Blt
• decreased circulating interleukin-6 level_Tnfrsf1a<tm1Blt>/Tnfrsf1a<+>
  http://metadb.riken.jp/0008597I129P2OlaHsdTnfrsf1atm1BltTnfrsf1aTnfrsf1atm1BltTnfrsf1a
• increased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm2Gkl>/Tnfrsf1a<+>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0009763I129SSvEvC57BL6JSJLTnfrsf1atm2GklTnfrsf1aTgVil1cre997Gum0Tnfrsf1atm2GklTnfrsf1aTgVil1cre997Gum
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm1Blt>/Tnfrsf1a<+>
  http://metadb.riken.jp/0003638I129P2OlaHsdTnfrsf1atm1BltTnfrsf1aTnfrsf1atm1BltTnfrsf1a
• tumor regression_Tnfrsf1a<tm4.1(TNFRSF1A)Gkl>/Tnfrsf1a<+>
  http://metadb.riken.jp/0010537I129P2OlaHsdTnfrsf1atm41TNFRSF1AGklTnfrsf1aTnfrsf1atm41TNFRSF1AGklTnfrsf1a
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm1Mak>/Tnfrsf1a<+>
  http://metadb.riken.jp/0003638I129S2SvPasTnfrsf1atm1MakTnfrsf1aTnfrsf1atm1MakTnfrsf1a
• increased sensitivity to induced cell death_Tnfrsf1a<tm1Blt>/Tnfrsf1a<tm1Blt>
  http://metadb.riken.jp/0008943I129P2OlaHsdTnfrsf1atm1BltTnfrsf1atm1BltTnfrsf1atm1Blt
• decreased sensitivity to induced morbidity/mortality_Tnfrsf1a<tm3.1Gkl>/Tnfrsf1a<tm3.1Gkl>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0009764I129P2OlaHsdC57BL6C57BL6JSJLTnfrsf1atm31GklTnfrsf1atm31GklTgVil1cre997Gum0TgVil1cre997GumTnfrsf1atm31Gkl
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm1Blt>/Tnfrsf1a<tm1Blt>
  http://metadb.riken.jp/0003638I129P2OlaHsdTnfrsf1atm1BltTnfrsf1atm1BltTnfrsf1atm1Blt
• increased susceptibility to bacterial infection induced morbidity/mortality_Tnfrsf1a<tm1Blt>/Tnfrsf1a<tm1Blt>
  http://metadb.riken.jp/0009788I129P2OlaHsdTnfrsf1atm1BltTnfrsf1atm1BltTnfrsf1atm1Blt
• impaired humoral immune response_Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>
  http://metadb.riken.jp/0020154I129S2SvPasTnfrsf1atm1MakTnfrsf1atm1MakTnfrsf1atm1Mak
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm3.1Gkl>/Tnfrsf1a<tm3.1Gkl>,Tg(Vil1-cre)997Gum/0
  http://metadb.riken.jp/0003638I129P2OlaHsdC57BL6C57BL6JSJLTnfrsf1atm31GklTnfrsf1atm31GklTgVil1cre997Gum0TgVil1cre997GumTnfrsf1atm31Gkl
• abnormal response/metabolism to endogenous compounds_Tnfrsf1a<tm1Imx>/Tnfrsf1a<+>
  http://metadb.riken.jp/0003638IC57BL6Tnfrsf1atm1ImxTnfrsf1aTnfrsf1aTnfrsf1atm1Imx

class

http://purl.org/net/cito/citesAsAuthority

• Tnfrsf1a<tm3.2Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5572950
• Tnfrsf1a<tm4.1(TNFRSF1A)Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5572951
• Tnfrsf1a<tm3.1Gkl>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5572949