increased sensitivity to xenobiotic induced morbidity/mortality_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>

http://metadb.riken.jp/0009766I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max

increased sensitivity to xenobiotic induced morbidity/mortality_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Fc receptor, IgE, low affinity II, alpha polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:95497
• immunoglobulin heavy constant gamma 1 (G1m marker)
  http://metadb.riken.jp/db/mgi_rdf/MGI:96446

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ighg1<tm1.1Pyu>|Fcer2a<tm1Max>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * BALB/cJ * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to xenobiotic induced morbidity/mortality
  http://purl.obolibrary.org/obo/MP_0009766

文献

http://purl.org/net/cito/citesAsAuthority

• Wolger. Lübben, et.al., IgE knock-in mice suggest a role for high levels of IgE in basophil-mediated active systemic anaphylaxis., European journal of immunology, 2013, 43
  http://rdf.ncbi.nlm.nih.gov/pubmed/23423996