Wolger. Lübben, et.al., IgE knock-in mice suggest a role for high levels of IgE in basophil-mediated active systemic anaphylaxis., European journal of immunology, 2013, 43

http://rdf.ncbi.nlm.nih.gov/pubmed/23423996

Wolger. Lübben, et.al., IgE knock-in mice suggest a role for high levels of IgE in basophil-mediated active systemic anaphylaxis., European journal of immunology, 2013, 43

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5502698

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased IgG2a level_Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0008500B6CCgIghg1tm11PyuIghg1tm11PyuIghg1Ighg1Ighg1tm11Pyu
• increased IgE level_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0002497B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu
• decreased IgG2c level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0008897I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• decreased body temperature_Fcer2a<tm1Max>/Fcer2a<tm1Max>
  http://metadb.riken.jp/0005534IC57BL6JFcer2atm1MaxFcer2atm1MaxFcer2atm1Max
• decreased IgG1 level_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0008495B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu
• increased IgG2a level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0008500I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• decreased IgG1 level_Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0008495B6CCgIghg1tm11PyuIghg1tm11PyuIghg1Ighg1Ighg1tm11Pyu
• increased IgG2a level_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0008500B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu
• increased IgE level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0002497I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• decreased body temperature_Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0005534B6CCgIghg1tm11PyuIghg1tm11PyuIghg1Ighg1Ighg1tm11Pyu
• decreased body temperature_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0005534B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu
• decreased body temperature_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0005534I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• increased susceptibility to type I hypersensitivity reaction_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0005596B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu
• decreased body temperature_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0005534I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• decreased IgG1 level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0008495I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• decreased IgG2c level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0008897I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• increased sensitivity to xenobiotic induced morbidity/mortality_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0009766I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• increased IgG2a level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0008500I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• increased sensitivity to xenobiotic induced morbidity/mortality_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0009766B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu
• decreased IgG2c level_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0008897B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu
• increased susceptibility to type I hypersensitivity reaction_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0005596I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• increased IgE level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0002497I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• abnormal immunoglobulin level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0002490I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• increased susceptibility to type I hypersensitivity reaction_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0005596I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• decreased IgG level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0001805I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuFcer2atm1Max
• increased susceptibility to type I hypersensitivity reaction_Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0005596B6CCgIghg1tm11PyuIghg1tm11PyuIghg1Ighg1Ighg1tm11Pyu
• increased IgE level_Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0002497B6CCgIghg1tm11PyuIghg1tm11PyuIghg1Ighg1Ighg1tm11Pyu
• decreased IgG level_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0001805I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• decreased IgG2c level_Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0008897B6CCgIghg1tm11PyuIghg1tm11PyuIghg1Ighg1Ighg1tm11Pyu
• increased sensitivity to xenobiotic induced morbidity/mortality_Fcer2a<tm1Max>/Fcer2a<tm1Max>,Ighg1<tm1.1Pyu>/Ighg1<+>
  http://metadb.riken.jp/0009766I129BALBcJC57BL6C57BL6JFcer2atm1MaxFcer2atm1MaxIghg1tm11PyuIghg1Ighg1tm11PyuFcer2atm1MaxIghg1
• increased IgG2b level_Ighg1<tm1.1Pyu>/Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/0008501B6CCgIghg1tm11PyuIghg1tm11PyuIghg1tm11PyuIghg1tm11Pyu

class

http://purl.org/net/cito/citesAsAuthority

• Ighg1<tm1.1Pyu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5502698