increased sensitivity to xenobiotic induced morbidity/mortality_Pcsk1<tm1Dfs>/Pcsk1<tm1Dfs>

http://metadb.riken.jp/0009766I129C57BL6JPcsk1tm1DfsPcsk1tm1DfsPcsk1tm1Dfs

increased sensitivity to xenobiotic induced morbidity/mortality_Pcsk1<tm1Dfs>/Pcsk1<tm1Dfs>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• proprotein convertase subtilisin/kexin type 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97511

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pcsk1<tm1Dfs>/Pcsk1<tm1Dfs>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pcsk1<tm1Dfs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased sensitivity to xenobiotic induced morbidity/mortality
  http://purl.obolibrary.org/obo/MP_0009766

文献

http://purl.org/net/cito/citesAsAuthority

• Sarah. Refaie, et.al., Disruption of proprotein convertase 1/3 (PC1/3) expression in mice causes innate immune defects and uncontrolled cytokine secretion., The Journal of biological chemistry, 2012, 287
  http://rdf.ncbi.nlm.nih.gov/pubmed/22396549