increased susceptibility to bacterial infection induced morbidity/mortality_Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

http://metadb.riken.jp/0009788I129S2SvPasTnfrsf1atm1MakTnfrsf1atm1MakTnfrsf1atm1Mak

increased susceptibility to bacterial infection induced morbidity/mortality_Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnfrsf1a<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to bacterial infection induced morbidity/mortality
  http://purl.obolibrary.org/obo/MP_0009788

文献

http://purl.org/net/cito/citesAsAuthority

• Filip. Van Hauwermeiren, et.al., Safe TNF-based antitumor therapy following p55TNFR reduction in intestinal epithelium., The Journal of clinical investigation, 2013, 123
  http://rdf.ncbi.nlm.nih.gov/pubmed/23676465
• Maria A. Ermolaeva, et.al., Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses., Nature immunology, 2008, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/18641654
• K. Pfeffer, et.al., Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection., Cell, 1993, 73
  http://rdf.ncbi.nlm.nih.gov/pubmed/8387893