abnormal dendritic spine morphology_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>,Tg(Nes-cre/Esr1*)4Ynj/0

http://metadb.riken.jp/0009936I129S6SvEvTacC57BL6NCrGtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj0GtROSA26Sortm1ACTBMap2k5EGFPZxiGtROSA26Sortm14CAGtdTomatoHzeTgNescreEsr14Ynj

abnormal dendritic spine morphology_Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>,Tg(Nes-cre/Esr1*)4Ynj/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 4, Yuh-Nung Jan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3765945
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>/Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>,Tg(Nes-cre/Esr1*)4Ynj/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<tm1(ACTB-Map2k5*/EGFP)Zxi>|Gt(ROSA)26Sor<tm14(CAG-tdTomato)Hze>|Tg(Nes-cre/Esr1*)4Ynj

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6NCr

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dendritic spine morphology
  http://purl.obolibrary.org/obo/MP_0009936

文献

http://purl.org/net/cito/citesAsAuthority

• Wenbin. Wang, et.al., Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, 34
  http://rdf.ncbi.nlm.nih.gov/pubmed/24501354