abnormal intestine physiology_Lgr4<tm1.1Knis>/Lgr4<tm1.1Knis>,Lgr5<tm2.1Cle>/Lgr5<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0010155I129P2OlaHsdC57BL6DBA2Lgr4tm11KnisLgr4tm11KnisLgr5tm21CleLgr5tm21CleTgVilcreERT223Syr0TgVilcreERT223SyrLgr5tm21CleLgr4tm11Knis

abnormal intestine physiology_Lgr4<tm1.1Knis>/Lgr4<tm1.1Knis>,Lgr5<tm2.1Cle>/Lgr5<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leucine rich repeat containing G protein coupled receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1341817
• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810
• leucine-rich repeat-containing G protein-coupled receptor 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1891468

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lgr4<tm1.1Knis>/Lgr4<tm1.1Knis>,Lgr5<tm2.1Cle>/Lgr5<tm2.1Cle>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil-cre/ERT2)23Syr|Lgr5<tm2.1Cle>|Lgr4<tm1.1Knis>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal intestine physiology
  http://purl.obolibrary.org/obo/MP_0010155

文献

http://purl.org/net/cito/citesAsAuthority

• Wim. de Lau, et.al., Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling., Nature, 2011, 476
  http://rdf.ncbi.nlm.nih.gov/pubmed/21727895