decreased brain cholesterol level_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0

http://metadb.riken.jp/0010161I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl

decreased brain cholesterol level_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion T29-1, Susumu Tonegawa
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177646
• low density lipoprotein receptor-related protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96828

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrp1<tm2Her>|Tg(Camk2a-cre)T29-1Stl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * BALB/c * C57BL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased brain cholesterol level
  http://purl.obolibrary.org/obo/MP_0010161

文献

http://purl.org/net/cito/citesAsAuthority

• Qiang. Liu, et.al., Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/21159977