Qiang. Liu, et.al., Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

http://rdf.ncbi.nlm.nih.gov/pubmed/21159977

Qiang. Liu, et.al., Neuronal LRP1 knockout in adult mice leads to impaired brain lipid metabolism and progressive, age-dependent synapse loss and neurodegeneration., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, 30

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• hyperactivity_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001399I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• impaired coordination_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001405I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• reduced long term potentiation_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001473I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• limb grasping_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001513I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• abnormal lipid level_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001547I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• brain inflammation_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0001847I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
他10件を見る
• abnormal associative learning_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002062I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• abnormal motor capabilities/coordination/movement_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002066I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• neurodegeneration_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0002229I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• abnormal nervous system physiology_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0003633I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• decreased triglyceride level_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0005318I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• impaired contextual conditioning behavior_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0009454I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• impaired cued conditioning behavior_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0009456I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• abnormal synapse morphology_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0009538I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• abnormal dendritic spine morphology_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0009936I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl
• decreased brain cholesterol level_Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Camk2a-cre)T29-1Stl/0
  http://metadb.riken.jp/0010161I129S7SvEvBrdBALBcC57BLLrp1tm2HerLrp1tm2HerTgCamk2acreT291Stl0Lrp1tm2HerTgCamk2acreT291Stl

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12013
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12013