decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0

http://metadb.riken.jp/0010169I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak

decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Junji Takeda
  http://metadb.riken.jp/db/mgi_rdf/MGI:3655253
• mitogen-activated protein kinase kinase kinase 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346877

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Map3k7<tm1Aki>|Tg(Lck-cre)1Jtak

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
  http://purl.obolibrary.org/obo/MP_0010169

文献

http://purl.org/net/cito/citesAsAuthority

• Hideki. Sanjo, et.al., Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ+ Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis., PloS one, 2015, 10
  http://rdf.ncbi.nlm.nih.gov/pubmed/26132627