Hideki. Sanjo, et.al., Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ+ Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis., PloS one, 2015, 10

http://rdf.ncbi.nlm.nih.gov/pubmed/26132627

Hideki. Sanjo, et.al., Conditional Deletion of TAK1 in T Cells Reveals a Pivotal Role of TCRαβ+ Intraepithelial Lymphocytes in Preventing Lymphopenia-Associated Colitis., PloS one, 2015, 10

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• decreased CD4-positive, CD25-positive, alpha-beta regulatory T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0010169I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal regulatory T cell physiology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0004946I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• decreased NK T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008040I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal T cell morphology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008037I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• increased interleukin-17 secretion_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008681I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• increased CD4-positive, alpha beta T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008074I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal regulatory T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0004972I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal intraepithelial T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008895I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal intestinal epithelium physiology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0014201I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal liver morphology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0000598I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal cytokine level_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008713I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• increased interferon-gamma secretion_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008566I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• colitis_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0002816I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal alpha-beta intraepithelial T cell morphology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008399I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• abnormal CD4-positive, alpha-beta T cell physiology_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0005463I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak
• increased gamma-delta intraepithelial T cell number_Map3k7<tm1Aki>/Map3k7<tm1Aki>,Tg(Lck-cre)1Jtak/0
  http://metadb.riken.jp/0008350I129P2OlaHsdC57BL6Map3k7tm1AkiMap3k7tm1AkiTgLckcre1Jtak0Map3k7tm1AkiTgLckcre1Jtak