increased T follicular helper cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?

http://metadb.riken.jp/0010186IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi

increased T follicular helper cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RING CCCH (C3H) domains 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2685397
• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• ring finger and CCCH-type zinc finger domains 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2442789

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rc3h1<tm1.1Mass>|Rc3h2<tm1c(KOMP)Wtsi>|Tg(Cd4-cre)1Cwi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T follicular helper cell number
  http://purl.obolibrary.org/obo/MP_0010186

文献

http://purl.org/net/cito/citesAsAuthority

• Katharina U. Vogel, et.al., Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation., Immunity, 2013, 38
  http://rdf.ncbi.nlm.nih.gov/pubmed/23583643