Katharina U. Vogel, et.al., Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation., Immunity, 2013, 38

http://rdf.ncbi.nlm.nih.gov/pubmed/23583643

Katharina U. Vogel, et.al., Roquin paralogs 1 and 2 redundantly repress the Icos and Ox40 costimulator mRNAs and control follicular helper T cell differentiation., Immunity, 2013, 38

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-CXADR*)Mass>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5509139
• Rc3h2<tm1c(KOMP)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5509140

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm1(CAG-CXADR*)Mass>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5509139
• Rc3h2<tm1c(KOMP)Wtsi>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5509140

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal spleen morphology_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0000689IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• enlarged spleen_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0000691IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• enlarged lymph nodes_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0000702IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• abnormal immune system cell morphology_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0000716IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• abnormal lung development_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001176IC57BL6NNMRIRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• abnormal lung development_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001176IC57BL6NRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
他19件を見る
• decreased body weight_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001262IC57BL6NNMRIRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• decreased body weight_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001262IC57BL6NRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• decreased body size_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001265IC57BL6NNMRIRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• decreased body size_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0001265IC57BL6NRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• abnormal immune system physiology_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0001790IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• abnormal spleen periarteriolar lymphoid sheath morphology_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0002358IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• abnormal B cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0002458IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• abnormal immune system organ morphology_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0002722IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• decreased T cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005018IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• increased T cell proliferation_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0005348IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• decreased CD4-positive, alpha beta T cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008075IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• decreased CD8-positive, alpha-beta T cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008079IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• increased germinal center B cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008177IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• abnormal spleen B cell follicle morphology_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0008470IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• increased T follicular helper cell number_Rc3h1<tm1.1Mass>/Rc3h1<tm1.1Mass>,Rc3h2<tm1c(KOMP)Wtsi>/Rc3h2<tm1c(KOMP)Wtsi>,Tg(Cd4-cre)1Cwi/?
  http://metadb.riken.jp/0010186IC57BL6NDBA2Rc3h1tm11MassRc3h1tm11MassRc3h2tm1cKOMPWtsiRc3h2tm1cKOMPWtsiTgCd4cre1CwiRc3h1tm11MassRc3h2tm1cKOMPWtsiTgCd4cre1Cwi
• abnormal lung alveolus development_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0010995IC57BL6NNMRIRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• abnormal lung alveolus development_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0010995IC57BL6NRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• postnatal lethality, incomplete penetrance_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0011086IC57BL6NNMRIRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi
• postnatal lethality, incomplete penetrance_Rc3h2<tm1a(KOMP)Wtsi>/Rc3h2<tm1a(KOMP)Wtsi>
  http://metadb.riken.jp/0011086IC57BL6NRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsiRc3h2tm1aKOMPWtsi