decreased T follicular helper cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>

http://metadb.riken.jp/0010187I129P2OlaHsd129X1SvJC57BL6Pik3cdtm21TnrPik3cdtm21TnrTnfrsf4tm2creNikTnfrsf4Tnfrsf4Tnfrsf4tm2creNikPik3cdtm21Tnr

decreased T follicular helper cell number_Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  http://metadb.riken.jp/db/mgi_rdf/MGI:1098211
• tumor necrosis factor receptor superfamily, member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:104512

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pik3cd<tm2.1Tnr>/Pik3cd<tm2.1Tnr>,Tnfrsf4<tm2(cre)Nik>/Tnfrsf4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnfrsf4<+>|Tnfrsf4<tm2(cre)Nik>|Pik3cd<tm2.1Tnr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased T follicular helper cell number
  http://purl.obolibrary.org/obo/MP_0010187

文献

http://purl.org/net/cito/citesAsAuthority

• Julia. Rolf, et.al., Phosphoinositide 3-kinase activity in T cells regulates the magnitude of the germinal center reaction., Journal of immunology (Baltimore, Md. : 1950), 2010, 185
  http://rdf.ncbi.nlm.nih.gov/pubmed/20826752