abnormal oligodendrocyte apoptosis_Tg(Tnf)6074Gkl/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>

http://metadb.riken.jp/0010205I129S2SvPasC57BL6CBATgTnf6074Gkl0Tnfrsf1btm1MwmTnfrsf1btm1MwmTnfrsf1btm1MwmTgTnf6074Gkl

abnormal oligodendrocyte apoptosis_Tg(Tnf)6074Gkl/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor receptor superfamily, member 1b
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314883
• transgene insertion 6074, George Kollias
  http://metadb.riken.jp/db/mgi_rdf/MGI:3766128

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Tnf)6074Gkl/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnfrsf1b<tm1Mwm>|Tg(Tnf)6074Gkl

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal oligodendrocyte apoptosis
  http://purl.obolibrary.org/obo/MP_0010205

文献

http://purl.org/net/cito/citesAsAuthority

• K. Akassoglou, et.al., Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy., The American journal of pathology, 1998, 153
  http://rdf.ncbi.nlm.nih.gov/pubmed/9736029