K. Akassoglou, et.al., Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy., The American journal of pathology, 1998, 153

http://rdf.ncbi.nlm.nih.gov/pubmed/9736029

K. Akassoglou, et.al., Oligodendrocyte apoptosis and primary demyelination induced by local TNF/p55TNF receptor signaling in the central nervous system of transgenic mice: models for multiple sclerosis with primary oligodendrogliopathy., The American journal of pathology, 1998, 153

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• CNS inflammation_Tg(Tnf)6074Gkl/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>
  http://metadb.riken.jp/0006082I129S2SvPasC57BL6CBATgTnf6074Gkl0Tnfrsf1btm1MwmTnfrsf1btm1MwmTnfrsf1btm1MwmTgTnf6074Gkl
• abnormal nervous system physiology_Tg(Gfap-TNF*)K21Gkl/0,Tnfrsf1a<tm1Blt>/Tnfrsf1a<+>
  http://metadb.riken.jp/0003633I129P2OlaHsdC57BL6CBATgGfapTNFK21Gkl0Tnfrsf1atm1BltTnfrsf1aTgGfapTNFK21GklTnfrsf1aTnfrsf1atm1Blt
• astrocytosis_Tg(Gfap-TNF*)K21Gkl/0
  http://metadb.riken.jp/0003354IC57BL6CBATgGfapTNFK21Gkl0TgGfapTNFK21Gkl
• demyelination_Tg(Tnf)6074Gkl/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>
  http://metadb.riken.jp/0000921I129S2SvPasC57BL6CBATgTnf6074Gkl0Tnfrsf1btm1MwmTnfrsf1btm1MwmTnfrsf1btm1MwmTgTnf6074Gkl
• abnormal astrocyte morphology_Tg(Gfap-TNF*)K21Gkl/0
  http://metadb.riken.jp/0002182IC57BL6CBATgGfapTNFK21Gkl0TgGfapTNFK21Gkl
• abnormal meninges morphology_Tg(Gfap-TNF*)K21Gkl/0
  http://metadb.riken.jp/0005623IC57BL6CBATgGfapTNFK21Gkl0TgGfapTNFK21Gkl
• axon degeneration_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0005405IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• abnormal oligodendrocyte apoptosis_Tg(Gfap-TNF*)K21Gkl/0
  http://metadb.riken.jp/0010205IC57BL6CBATgGfapTNFK21Gkl0TgGfapTNFK21Gkl
• abnormal oligodendrocyte apoptosis_Tg(Tnf)6074Gkl/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>
  http://metadb.riken.jp/0010205I129S2SvPasC57BL6CBATgTnf6074Gkl0Tnfrsf1btm1MwmTnfrsf1btm1MwmTnfrsf1btm1MwmTgTnf6074Gkl
• abnormal astrocyte morphology_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0002182IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• demyelination_Tg(Gfap-TNF*)K21Gkl/0,Tnfrsf1a<tm1Blt>/Tnfrsf1a<+>
  http://metadb.riken.jp/0000921I129P2OlaHsdC57BL6CBATgGfapTNFK21Gkl0Tnfrsf1atm1BltTnfrsf1aTgGfapTNFK21GklTnfrsf1aTnfrsf1atm1Blt
• abnormal nervous system physiology_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0003633IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• demyelination_Tg(Gfap-TNF*)K21Gkl/0
  http://metadb.riken.jp/0000921IC57BL6CBATgGfapTNFK21Gkl0TgGfapTNFK21Gkl
• abnormal oligodendrocyte apoptosis_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0010205IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• brain inflammation_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0001847IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• abnormal blood-brain barrier function_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0005167IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• demyelination_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0000921IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• axon degeneration_Tg(Gfap-TNF*)K21Gkl/0
  http://metadb.riken.jp/0005405IC57BL6CBATgGfapTNFK21Gkl0TgGfapTNFK21Gkl
• abnormal meninges morphology_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0005623IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• abnormal microglial cell morphology_Tg(Tnf)6074Gkl/0
  http://metadb.riken.jp/0000136IC57BL6CBATgTnf6074Gkl0TgTnf6074Gkl
• CNS inflammation_Tg(Gfap-TNF*)K21Gkl/0
  http://metadb.riken.jp/0006082IC57BL6CBATgGfapTNFK21Gkl0TgGfapTNFK21Gkl