increased melanoma incidence_Braf<tm1Cpri>/Braf<tm1Cpri>,Tg(Tyr-cre/ERT2)1Lru/0

http://metadb.riken.jp/0010275I129P2OlaHsdC57BL6DBA2Braftm1CpriBraftm1CpriTgTyrcreERT21Lru0Braftm1CpriTgTyrcreERT21Lru

increased melanoma incidence_Braf<tm1Cpri>/Braf<tm1Cpri>,Tg(Tyr-cre/ERT2)1Lru/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Braf transforming gene
  http://metadb.riken.jp/db/mgi_rdf/MGI:88190
• transgene insertion 1, Lionel Larue
  http://metadb.riken.jp/db/mgi_rdf/MGI:3617508

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Braf<tm1Cpri>/Braf<tm1Cpri>,Tg(Tyr-cre/ERT2)1Lru/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Braf<tm1Cpri>|Tg(Tyr-cre/ERT2)1Lru

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased melanoma incidence
  http://purl.obolibrary.org/obo/MP_0010275

文献

http://purl.org/net/cito/citesAsAuthority

• Nathalie. Dhomen, et.al., Oncogenic Braf induces melanocyte senescence and melanoma in mice., Cancer cell, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19345328