Nathalie. Dhomen, et.al., Oncogenic Braf induces melanocyte senescence and melanoma in mice., Cancer cell, 2009, 15

http://rdf.ncbi.nlm.nih.gov/pubmed/19345328

Nathalie. Dhomen, et.al., Oncogenic Braf induces melanocyte senescence and melanoma in mice., Cancer cell, 2009, 15

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased incidence of tumors by chemical induction_Braf<tm1Cpri>/Braf<tm1Cpri>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0004499I129Sv129P2OlaHsdC57BL6DBA2SJLBraftm1CpriBraftm1CpriCdkn2atm1RdpCdkn2atm1RdpTgTyrcreERT21Lru0Braftm1CpriCdkn2atm1RdpTgTyrcreERT21Lru
• increased melanoma incidence_Braf<tm1Cpri>/Braf<tm1Cpri>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0010275I129P2OlaHsdC57BL6DBA2Braftm1CpriBraftm1CpriTgTyrcreERT21Lru0Braftm1CpriTgTyrcreERT21Lru
• spontaneous skin ulceration_Braf<tm1Cpri>/Braf<tm1Cpri>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0001209I129P2OlaHsdC57BL6DBA2Braftm1CpriBraftm1CpriTgTyrcreERT21Lru0Braftm1CpriTgTyrcreERT21Lru
• increased skin tumor incidence_Braf<tm1Cpri>/Braf<tm1Cpri>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0010300I129P2OlaHsdC57BL6DBA2Braftm1CpriBraftm1CpriTgTyrcreERT21Lru0Braftm1CpriTgTyrcreERT21Lru
• increased melanoma incidence_Braf<tm1Cpri>/Braf<tm1Cpri>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0010275I129Sv129P2OlaHsdC57BL6DBA2SJLBraftm1CpriBraftm1CpriCdkn2atm1RdpCdkn2atm1RdpTgTyrcreERT21Lru0Braftm1CpriCdkn2atm1RdpTgTyrcreERT21Lru
• hyperpigmentation_Braf<tm1Cpri>/Braf<tm1Cpri>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0001188I129P2OlaHsdC57BL6DBA2Braftm1CpriBraftm1CpriTgTyrcreERT21Lru0Braftm1CpriTgTyrcreERT21Lru
• increased skin tumor incidence_Braf<tm1Cpri>/Braf<tm1Cpri>,Cdkn2a<tm1Rdp>/Cdkn2a<tm1Rdp>,Tg(Tyr-cre/ERT2)1Lru/0
  http://metadb.riken.jp/0010300I129Sv129P2OlaHsdC57BL6DBA2SJLBraftm1CpriBraftm1CpriCdkn2atm1RdpCdkn2atm1RdpTgTyrcreERT21Lru0Braftm1CpriCdkn2atm1RdpTgTyrcreERT21Lru