increased gastrointestinal tumor incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>

http://metadb.riken.jp/0010279I129P2OlaHsd129S4SvJae129S6SvEvTacKrastm4TyjKrasTrp53tm1BrnTrp53tm1BrnKrt19tm1creERTGguKrt19Krt19Trp53tm1BrnKrt19tm1creERTGguKrasKrastm4Tyj

increased gastrointestinal tumor incidence_Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• keratin 19
  http://metadb.riken.jp/db/mgi_rdf/MGI:96693
• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Trp53<tm1Brn>/Trp53<tm1Brn>,Krt19<tm1(cre/ERT)Ggu>/Krt19<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Krt19<+>|Trp53<tm1Brn>|Krt19<tm1(cre/ERT)Ggu>|Kras<+>|Kras<tm4Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * 129S6/SvEvTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased gastrointestinal tumor incidence
  http://purl.obolibrary.org/obo/MP_0010279

文献

http://purl.org/net/cito/citesAsAuthority

• Gaëlle. Lapouge, et.al., Identifying the cellular origin of squamous skin tumors., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21502497