increased gastrointestinal tumor incidence_Apc<tm1Rsmi>/Apc<+>,Ctnnb1<tm1Wvv>/Ctnnb1<+>,Tg(Fabp1-cre)1Jig/?

http://metadb.riken.jp/0010279I129P2OlaHsdC57BL6JFVBNApctm1RsmiApcCtnnb1tm1WvvCtnnb1TgFabp1cre1JigTgFabp1cre1JigCtnnb1tm1WvvApcCtnnb1Apctm1Rsmi

increased gastrointestinal tumor incidence_Apc<tm1Rsmi>/Apc<+>,Ctnnb1<tm1Wvv>/Ctnnb1<+>,Tg(Fabp1-cre)1Jig/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey I Gordon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447210
• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm1Rsmi>/Apc<+>,Ctnnb1<tm1Wvv>/Ctnnb1<+>,Tg(Fabp1-cre)1Jig/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Fabp1-cre)1Jig|Ctnnb1<tm1Wvv>|Apc<+>|Ctnnb1<+>|Apc<tm1Rsmi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased gastrointestinal tumor incidence
  http://purl.obolibrary.org/obo/MP_0010279

文献

http://purl.org/net/cito/citesAsAuthority

• Wendy. van Veelen, et.al., β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis., Gut, 2011, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/21307168