Wendy. van Veelen, et.al., β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis., Gut, 2011, 60

http://rdf.ncbi.nlm.nih.gov/pubmed/21307168

Wendy. van Veelen, et.al., β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis., Gut, 2011, 60

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Ctnnb1<tm1.1Wvv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430597
• Ctnnb1<tm1Wvv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430602
• Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430598

class

http://purl.org/net/cito/citesAsAuthority

• Ctnnb1<tm1.1Wvv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430597
• Ctnnb1<tm1Wvv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430602
• Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5430598

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• microcephaly_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0000433I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• rostral body truncation_Apc<tm1Rak>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0012157I129P2OlaHsdC57BL6JApctm1RakApcCtnnb1tm12WvvCtnnb1Ctnnb1Apctm1RakApcCtnnb1tm12Wvv
• increased intestinal adenocarcinoma incidence_Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0002957I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1Ctnnb1Ctnnb1tm12Wvv
• increased gastrointestinal tumor incidence_Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0010279I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1Ctnnb1Ctnnb1tm12Wvv
• abnormal head shape_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0011495I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• embryonic lethality, complete penetrance_Apc<tm1Rak>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6JApctm1RakApcCtnnb1tm12WvvCtnnb1Ctnnb1Apctm1RakApcCtnnb1tm12Wvv
• abnormal tongue morphology_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0000762I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• abnormal nasal capsule morphology_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0004726I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• rostral body truncation_Apc<tm2Rfo>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0012157I129P2OlaHsdC57BL6JApctm2RfoApcCtnnb1tm12WvvCtnnb1ApcCtnnb1tm12WvvApctm2RfoCtnnb1
• abnormal maxillary prominence morphology_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0010940I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• increased gastrointestinal tumor incidence_Apc<tm1Rsmi>/Apc<+>,Ctnnb1<tm1Wvv>/Ctnnb1<+>,Tg(Fabp1-cre)1Jig/?
  http://metadb.riken.jp/0010279I129P2OlaHsdC57BL6JFVBNApctm1RsmiApcCtnnb1tm1WvvCtnnb1TgFabp1cre1JigTgFabp1cre1JigCtnnb1tm1WvvApcCtnnb1Apctm1Rsmi
• abnormal craniofacial development_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0003935I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• abnormal head morphology_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0000432I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• increased intestinal adenoma incidence_Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0002404I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1Ctnnb1Ctnnb1tm12Wvv
• abnormal telencephalon development_Apc<tm1Rak>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0000934I129P2OlaHsdC57BL6JApctm1RakApcCtnnb1tm12WvvCtnnb1Ctnnb1Apctm1RakApcCtnnb1tm12Wvv
• abnormal mandibular prominence morphology_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0010939I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• perinatal lethality, complete penetrance_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0011089I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• embryonic lethality, complete penetrance_Apc<tm2Rfo>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>
  http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6JApctm2RfoApcCtnnb1tm12WvvCtnnb1ApcCtnnb1tm12WvvApctm2RfoCtnnb1
• abnormal maxilla morphology_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0000455I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• abnormal cranium morphology_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0000438I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv
• facial cleft_Ctnnb1<tm1.2Wvv>/Ctnnb1<tm1.2Wvv>
  http://metadb.riken.jp/0008797I129P2OlaHsdC57BL6JCtnnb1tm12WvvCtnnb1tm12WvvCtnnb1tm12Wvv