increased gastrointestinal tumor incidence_Kit<tm5.1Bsm>/Kit<+>

http://metadb.riken.jp/0010279I129S1SvC57BL6JFVBNKittm51BsmKitKitKittm51Bsm

increased gastrointestinal tumor incidence_Kit<tm5.1Bsm>/Kit<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• KIT proto-oncogene receptor tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96677

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kit<tm5.1Bsm>/Kit<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kit<+>|Kit<tm5.1Bsm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased gastrointestinal tumor incidence
  http://purl.obolibrary.org/obo/MP_0010279

文献

http://purl.org/net/cito/citesAsAuthority

• Benedikt. Bosbach, et.al., Imatinib resistance and microcytic erythrocytosis in a KitV558Δ;T669I/+ gatekeeper-mutant mouse model of gastrointestinal stromal tumor., Proceedings of the National Academy of Sciences of the United States of America, 2012, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/22652566