increased skeletal tumor incidence_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Col1a1-cre)1Kry/0

http://metadb.riken.jp/0010280I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1aTgCol1a1cre1Kry0Prkar1atm12LskPrkar1aTgCol1a1cre1Kry

increased skeletal tumor incidence_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Col1a1-cre)1Kry/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Gerard Karsenty
  http://metadb.riken.jp/db/mgi_rdf/MGI:3041865
• protein kinase, cAMP dependent regulatory, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:104878

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Col1a1-cre)1Kry/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prkar1a<tm1.2Lsk>|Prkar1a<+>|Tg(Col1a1-cre)1Kry

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skeletal tumor incidence
  http://purl.obolibrary.org/obo/MP_0010280

文献

http://purl.org/net/cito/citesAsAuthority

• Sam D. Molyneux, et.al., Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20697156