Sam D. Molyneux, et.al., Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice., The Journal of clinical investigation, 2010, 120

http://rdf.ncbi.nlm.nih.gov/pubmed/20697156

Sam D. Molyneux, et.al., Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice., The Journal of clinical investigation, 2010, 120

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Bglap2-TAg)1Rkho
  http://metadb.riken.jp/db/mgi_rdf/MGI:5796023

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased osteosarcoma incidence_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Bglap2-TAg)1Rkho/0,Tg(Col1a1-cre)1Kry/0
  http://metadb.riken.jp/0003789I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1aTgBglap2TAg1Rkho0TgCol1a1cre1Kry0TgCol1a1cre1KryTgBglap2TAg1RkhoPrkar1aPrkar1atm12Lsk
• premature death_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Bglap2-TAg)1Rkho/0,Tg(Col1a1-cre)1Kry/0
  http://metadb.riken.jp/0002083I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1aTgBglap2TAg1Rkho0TgCol1a1cre1Kry0TgCol1a1cre1KryTgBglap2TAg1RkhoPrkar1aPrkar1atm12Lsk
• increased skeletal tumor incidence_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Col1a1-cre)1Kry/0
  http://metadb.riken.jp/0010280I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1aTgCol1a1cre1Kry0Prkar1atm12LskPrkar1aTgCol1a1cre1Kry
• neonatal lethality, complete penetrance_Prkar1a<tm1.2Lsk>/Prkar1a<tm1.2Lsk>,Tg(Col1a1-cre)1Kry/0
  http://metadb.riken.jp/0011087I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1atm12LskTgCol1a1cre1Kry0TgCol1a1cre1KryPrkar1atm12Lsk
• increased metastatic potential_Tg(Bglap2-TAg)1Rkho/0
  http://metadb.riken.jp/0001272FVBNTgBglap2TAg1RkhoTgBglap2TAg1Rkho0TgBglap2TAg1Rkho
• premature death_Tg(Bglap2-TAg)1Rkho/0
  http://metadb.riken.jp/0002083FVBNTgBglap2TAg1RkhoTgBglap2TAg1Rkho0TgBglap2TAg1Rkho
• increased skeletal tumor incidence_Tg(Bglap2-TAg)1Rkho/0
  http://metadb.riken.jp/0010280FVBNTgBglap2TAg1RkhoTgBglap2TAg1Rkho0TgBglap2TAg1Rkho
• abnormal bone remodeling_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Col1a1-cre)1Kry/0
  http://metadb.riken.jp/0002998I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1aTgCol1a1cre1Kry0Prkar1atm12LskPrkar1aTgCol1a1cre1Kry
• paralysis_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Bglap2-TAg)1Rkho/0,Tg(Col1a1-cre)1Kry/0
  http://metadb.riken.jp/0000753I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1aTgBglap2TAg1Rkho0TgCol1a1cre1Kry0TgCol1a1cre1KryTgBglap2TAg1RkhoPrkar1aPrkar1atm12Lsk
• abnormal motor capabilities/coordination/movement_Prkar1a<tm1.2Lsk>/Prkar1a<+>,Tg(Bglap2-TAg)1Rkho/0,Tg(Col1a1-cre)1Kry/0
  http://metadb.riken.jp/0002066I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1aTgBglap2TAg1Rkho0TgCol1a1cre1Kry0TgCol1a1cre1KryTgBglap2TAg1RkhoPrkar1aPrkar1atm12Lsk
• increased osteosarcoma incidence_Tg(Bglap2-TAg)1Rkho/0
  http://metadb.riken.jp/0003789FVBNTgBglap2TAg1RkhoTgBglap2TAg1Rkho0TgBglap2TAg1Rkho

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Bglap2-TAg)1Rkho
  http://metadb.riken.jp/db/mgi_rdf/MGI:5796023

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD21367
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD21367