increased skin tumor incidence_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tg(Krt1-15-cre/PGR)22Cot/0

http://metadb.riken.jp/0010300I129S1Sv129X1SvJC57BL6SJLChuktm1YhuChuktm1YhuTgKrt115crePGR22Cot0TgKrt115crePGR22CotChuktm1Yhu

increased skin tumor incidence_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tg(Krt1-15-cre/PGR)22Cot/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 22, George Cotsarelis
  http://metadb.riken.jp/db/mgi_rdf/MGI:3511784
• conserved helix-loop-helix ubiquitous kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99484

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tg(Krt1-15-cre/PGR)22Cot/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Krt1-15-cre/PGR)22Cot|Chuk<tm1Yhu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin tumor incidence
  http://purl.obolibrary.org/obo/MP_0010300

文献

http://purl.org/net/cito/citesAsAuthority

• Bigang. Liu, et.al., IKKalpha is required to maintain skin homeostasis and prevent skin cancer., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18772111