increased skin tumor incidence_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tg(Krt1-5-cre/ERT)1Ipc/0

http://metadb.riken.jp/0010300I129S1Sv129X1SvJC57BL6SJLChuktm1YhuChuktm1YhuTgKrt15creERT1Ipc0Chuktm1YhuTgKrt15creERT1Ipc

increased skin tumor incidence_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tg(Krt1-5-cre/ERT)1Ipc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• conserved helix-loop-helix ubiquitous kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99484
• transgene insertion 1, I Pierre Chambon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177424

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chuk<tm1Yhu>/Chuk<tm1Yhu>,Tg(Krt1-5-cre/ERT)1Ipc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chuk<tm1Yhu>|Tg(Krt1-5-cre/ERT)1Ipc

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased skin tumor incidence
  http://purl.obolibrary.org/obo/MP_0010300

文献

http://purl.org/net/cito/citesAsAuthority

• Bigang. Liu, et.al., IKKalpha is required to maintain skin homeostasis and prevent skin cancer., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18772111